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About Us

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Overview

Neuromusculoskeletal disorders constitute some of the most impactful challenges for the aged. The disease burden of these disorders, including osteoarthritis, osteoporosis, low-back pain, muscular defects such as sarcopenia and volumetric muscle loss, and tendon, vascular, and peripheral nerve injuries, and others, is well recognized, as they represent the primary cause of physical disability and severely compromise mobility, functionality, and quality of life.

Center for Neuromusculoskeletal Restorative Medicine (CNRM) is a multi-disciplinary, international consortium devoted to the application of convergent principles and technologies of biomedical science and engineering to restore structure and function to neuromusculoskeletal tissues and organs injured, diseased and degenerated due to aging, for the maintenance of mobility and enhancement of quality of life through biomedical research and development.

The Center based at the Hong Kong Science and Technology Park (HKSTP), combines the talents and expertise in stem cells, biomaterials, 3D bioprinting, tissue engineering, and personalized and translational medicine from The Chinese University of Hong Kong (CUHK) and the Karolinska Institutet (KI).

The Center will support five research programmes:

Stem Cells and Cell-Based Therapies;
Tissue Engineering and 3D Microtissue Modeling;
Cellular and Molecular Mechanisms;
Preclinical and Clinical Translation; and
Enabling Technologies,

Our objectives

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Conduct state of the art, multi-disciplinary research on neuromusculoskeletal regeneration, addressing diseases that affect skeletal tissues, including cartilage, tendon and the joint complex, skeletal muscle, vascular tissues, and central and peripheral nervous system of extremities
Recruit existing and new investigators to enable a synergistic “team science” approach for neuromusculoskeletal regeneration
Encourage and support the development of innovative scientific ideas through seed funding mechanisms and enabling technologies
Provide training and education for future leaders focused in neuromusculoskeletal engineering and regeneration, including laboratory and clinical research opportunities, seminar series, and visiting scholar programs
Foster the translation of basic science discoveries into drug development and clinically viable treatments
Leverage our existing and future basic/clinical research team and partnerships with pharmaceutical and biotechnology industries to facilitate innovation and transform patient care
Conduct state of the art, multi-disciplinary research on neuromusculoskeletal regeneration, addressing diseases that affect skeletal tissues, including cartilage, tendon and the joint complex, skeletal muscle, vascular tissues, and central and peripheral nervous system of extremities
Recruit existing and new investigators to enable a synergistic “team science” approach for neuromusculoskeletal regeneration
Encourage and support the development of innovative scientific ideas through seed funding mechanisms and enabling technologies
Provide training and education for future leaders focused in neuromusculoskeletal engineering and regeneration, including laboratory and clinical research opportunities, seminar series, and visiting scholar programs
Foster the translation of basic science discoveries into drug development and clinically viable treatments
Leverage our existing and future basic/clinical research team and partnerships with pharmaceutical and biotechnology industries to facilitate innovation and transform patient care
The initiatives for setting up the CNRM, with its thematic & multi-disciplinary nature and collaboration between the two world-class research institutions, present a very unique strength to accelerate R&D breakthrough in neuromusculoskeletal disease. It will certainly strengthen the stature and commitment of Hong Kong as an advanced R&D hub in the region.

Prof. Yung Shu-hang Patrick, MH JP
Director of CNRM